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Zhang, Zhuzhu
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Brain development and disorders
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Psychiatric disorders
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overview
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My research lies at the intersection of genomics, neuroscience, and bioinformatics. Our lab delves into the complexities of epigenomic regulation in the brain, influenced by both inherent genetic factors and life experiences. Developing and utilizing innovative single-cell multi-omics and spatial genomics methodologies, along with neural circuit analysis and integrative computational approaches, we interrogate dynamic epigenomic and gene regulation at the levels of individual cell types, brain regions, and neural circuits. Additionally, we aim to elucidate how life experiences interplay with individuals' genetics to leave enduring imprints on epigenetic regulation, thereby affecting behavior and the propensity for brain disorders.
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Zhang, Zhuzhu